Research Progress on a SARS-CoV-2 Vaccine in China
نویسندگان
چکیده
Although many countries have controlled the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through strict management, there are still with record-breaking numbers new cases. Therefore, it is very important to develop a vaccine that can cause wide cross reactivity in clinical trials. At present, more than 90 vaccines entering trials and progressing smoothly, including inactivated vaccines, adenovirus-vectored other types vaccines. Here, we review summarize efficacy potential threats SARS-CoV-2 vaccine. We reviewed whole-virus adenovirus-subunit recombinant protein discussed positive negative consequences However, heated debates on mechanism, effectiveness, breadth protection. In conclusion, this study predict risk outbreaks future by discussing research development status China countries. Looking future, mine large amount data generated universal ensure these programs equally useful face mutations.
منابع مشابه
Design of a Multi-epitope Peptide Vaccine against SARS-CoV-2 based on Immunoinformatics Data
Background and purpose: In 2019, the world has witnessed the emergence of a virus that caused acute respiratory distress syndrome in human with high mortality rates (approximately 3.7%). So far, no effective treatment has been proven against COVID-19. This study aimed at designing a multi-epitope vaccine combining several T-cell and B-cell epitopes of the SARS-CoV-2. Materials and methods: Bas...
متن کاملIn silico design a multivalent epitope vaccine against SARS-CoV-2 for Iranian populations
Background: Due to high genetic variation in human leukocyte antigen )HLA( alleles, epitope-based vaccines don’t show equal efficacy in different human populations. therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity as well as conservancy level from SARS-CoV...
متن کاملSARS-CoV-2: A Review Of Present & Future Perspectives
As the dawn of this new decade has begun, we have faced our arch-nemesis right at the start in the form of Coronavirus also known as COVID-19. Since its origin from Wuhan, China, it has been declared a pandemic and has effected several countries worldwide. This review article summarizes all the research, techniques, strategies, and treatment methodologies that are taking place internationally i...
متن کاملSARS-CoV-2 infection: its psychiatric manifestations
Background: The clinical presentation of SARS-CoV-2 infection was initially dominated by respiratory symptoms. However the clinical spectrum is wide and neuropsychiatric syndromes are also a source of medical concern. Our aims are to present an atypical clinical presentation of SARS-CoV-2 infection characterized by auditory hallucinations and unusual behavior and to emphasize the diversity of ...
متن کاملمروری به بررسی ایمونولوژیکی SARS-Cov-2
زمینه و هدف بیماری کووید-19 یک بیماری عفونی بهشدت مسری میباشد که توسط یک کروناویروس جدید ایجاد میشود که میتواند از انسان به انسان از طریق تماس نزدیک منتقل شود. هدف از مطالعه حاضر بررسی اطلاعات جدید در زمینه ایمونولوژی کووید-19 میباشد. مواد و روشها در مطالعه مروری حاضر، از موتورهای جستجوی Google و Google Scholar و مقالات نمایه شده در پایگاههای علمی معتبر بینالمللی از جمله Pub Med، MedLi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biosciences and Medicines
سال: 2021
ISSN: ['2327-509X', '2327-5081']
DOI: https://doi.org/10.4236/jbm.2021.911008